Open Access: Koste es, was es wolle?

MEN-2-Syndrom: Was gibt es Neues?

Multiple Endocrine Neoplasia Type 2 (MEN-2): An Update. Multiple endocrine neoplasia type 2 (MEN-2) is an autosomal dominant hereditary cancer syndrome. The disorder is caused by missense mutations of the RET proto-oncogene that result in their gain of function. Three distinct clinical subtypes of MEN-2 are characterized: MEN-2A, MEN-2B, and familial MTC (FMTC). The precise RET mutations may su...

Beethoven (Muss es sein? Es muss sein!)

"The child is father of the man" is the philosophy of the paediatrician, hence the recent trend of intense interest in child development, which embraces the study of factors which influence the growth of the body, mind, personality and spirit from conception to maturity and ultimate achievement. As practitioners of medicine it is natural that much of our effort should be used in the diagnosis a...

Online-Algorithmen: Was ist es wert, die Zukunft zu kennen?

In diesem Jahr möchte ich nach längerer Pause wieder in den Skiurlaub fahren. Leider sind mir meine alten Skier zu klein, und so stehe ich vor der Frage, ob ich mir Skier leihen oder doch lieber kaufen soll. Wenn ich sie mir leihe, so muss ich pro Tag 10 Euro Leihgebühr zahlen. Für die 7 Tage meines Urlaubs würde ich also 70 Euro zahlen. Wenn ich mir Skier kaufe, so fallen Kosten von 140 Euro a...

Aza-Wittig access to chiral imidazol(in)es.

2-Imidazolines and imidazoles have been accessed by an aza-Wittig sequence featuring novel N-acylation methodology for sulfonamides and optimized conditions for ring closure.

Upwinding Sour es at Interfa es in onservation laws